I would recommend you focus on a couple neighborhoods that you would like to live in; and familiarize yourself with that market. Some may tell you that you can systematize anything, but the problem is, every individual home is different (even the newer cookie cutter neighborhoods).
Focus on two or three neighborhoods and know what a good deal looks like in those pockets.
I would also temper your expectations as far as finding a lot of equity on MLS. This is a competitive sellers market at the moment with a lot of players working the MLS, you can get some nice base hits here and there, but I don't know of anyone that's hit a homerun buying on the market lately.
If you are good with your numbers, you're already ahead of the game. The problem is, you can't put the unique challenges that each single family home has on a spread sheet. You can set some alerts and presets that will send you houses, but you have to be able to look at them and know if its a deal or not.
Just my two cents!