I am not familiar with your market, but I focus primarily on retail brokerage so I may be able to help. Our business is known for the saying "Location, location, location!" because it is the only thing you can't change about real estate. With retail what surrounds you is everything. If you are aiming for the quality national credit tenants they typically want co-tenancy with other quality retailers. Is the area surrounded by similar retailers or are many of the adjacent buildings vacant? What do the demographics look like? If the area is not a true "retail corridor" your pool of potential tenants will be limited to mom & pop shops, which can no doubt be fantastic tenants, but are less desirable due to the associated risk.
If your budget only allows you to buy a property in an undesirable area it may be better to save up until you can afford a nicer area or look at alternative investments. Don't be in a rush and most importantly know your area like the back of your hand before buying so you know who your potential tenants are.