@Jack B.
I've had tenants in MF complain about weed smoke entering their units from outside patio below. As an SFR that concern may apply to neighbors if smoking outdoors or it may effect the odor of your house if smoking indoors. It could be expensive to get that odor out, ie, new interior paint job. If not smoking it indoors that issue isn't as much concern. However, I'd check whether growing would imbue any odor on your house. Id also check whether there's any increased risk of fire, what effect the added load might have on your electrical system. As a side note, a friend rented to a section8 tenant that turned his house into a grow operation without his knowledge or permission. According to him the tenant moved out in the middle of the night and left him with an absolute disaster from the clandestine grow operation. I don't remember any other details except the damage was extensive and costly. I remember how extremely upset he was about it. This tenant seems to be more upstanding and honest. However, still do your due diligence on the potential for damage, and the potential for infringing on neighbors, the potential for fire or water damage, or smoke or odor damage, before deciding.
