The pros is that the cost of buying real estate is cheaper and so are the taxes. They probably have less earthquakes too. They may suffer from other weather related problems like tornados and hail though so check insurance rates.
The cons is that you can get ripped off a lot easier and for a lot more money since you are not there to monitor what is going on. Contractors can get into disputes and make it hard for you to decipher who is telling the truth and who is not. Traveling back and forth can wear you out. You may not know the culture, law of the states, or ideal neighborhoods well.
You may want to get a project manager along with a general contractor to assist on the renovations. Plus they should assist in cutting your travel time.
Its good to have a discount legal service to back you up and or a local lawyer.
If you are not going to physically see the property then I suggest hiring wegolook.com, freelance photographer, friend or family to take videos or pictures front, back, inside, outside of the homes and the neighborhood. Tell them not to doctor up the pictures with photoshop either. I would not rely on the pictures from realtors and wholesalers alone because they are trying to sell the property to you. They may use a wide angle lens and add more light so the place looks larger than it is. A lot of times some will not photograph everything.