I invested out of state but I did not relocate. If you want to go that route you probably should do a lot of research and networking first before taking the plunge. If you need to stay close to family and friends then I would probably look into a states nearby that was hiring people in the same field that I work in. Next I would go to the census and see what the employment, population, avg income, taxes, incentives, eviction laws, etc are going to be. I would look for their local real estate meetups, reias, and city planning offices to get a feel of what neighborhood is popular or on the come up. Plus it helps to know the local laws and contractors out there as well. Two other groups who know a lot are taxi drivers and police officers. If you buy them a donut, pizza, or cookies they will be your friend for life. Plus they know about where the crime is that the papers don't always know. They also know about new developments too.