Indio is considering changing their ordinance regarding music/noise outside at vacation rentals. 

I will say if they are being excessively noisy, politely asking them to reduce noise where possible would be reasonable.

Here where they failed,  their online customer service is a joke, took 3 calls over 3 days to get someone that I could understand, there background noise wasn't overly loud and there systems were working properly.  

Other things to consider would be insurance implications (make sure your policy will cover you, and you'll probably want extra liability coverage), zoning (most likely this would be allowable as a special or conditional use within a single family home zoning but you'll want to check that for your specific location for sure), potential noise complaints/issues with neighbors, required permits, annual inspections by the regulatory body, contingency plan for if the neighbor goes out of business/ files bankruptcy, etc. 

There can also be other issues...noise, leaks, trash out on the wrong day, storing things on the balconies, parking,  and on and on that you won't find in single family.  

This could include guidelines on noise levels, parking, garbage disposal, and other common concerns.

.- Grind to find opportunities to JV with my new investor friends.- Partner with family sooner.

I've been on home boards for 20 years now, and there have been 3 or 4 times that people have come in about scratching pest noises that follow them, and in every case, that person has been hallucinating, and in some cases, it's progressed to a clear psychotic break, going from "there are mice I can't get rid of" to "the government/my ex husband is sending in spy mice to get me."

Discussions are in the works to legalize it and regulate it, but I have my doubts it will ever happen.City of Las Vegas - Short-Term Residential Rentals are limited to owner-occupied homes that are three bedrooms or less, are at least 660 feet from another short-term rental, and must comply with licensing, noise and parking regulations.

Pertinent amenities like blackout curtains and noise machines to improve sleep for travel nurses.