Hi Jason,
Love, love, love Santa Cruz!!!
But, alas, I'm currently based in MI. Also, I've finally concluded that my ROI growth is too slow going here so I'm going to be exiting and expanding. To that end, I'm looking to invest in MN IL OH, TN, AZ TX, VA NC SC GA FL, and/or WA.
It's a lot of research but I enjoy it. I'm data driven, using blockgroup-level census demographics and county-level parcel data. ESRI's ArcGIS software is a powerhorse! I also love satellite imagery (but ENVI, Erdas is better for those data, currently) and LiDAR (eCog).
Based on what I'm seeing so far, if you decide on out-of-state then I suggest taking your cues from the growth of metro areas. For instance, is any given metro area (surrounding cities that support a main city, or two) really growing when you compare it to any other metro area?
So, when scouting new areas, we all know (thanks to BP!) that we need to look for areas with strong job growth/decreasing unemployment trends. Job growth and high employment are not necessarily the same thing as migration into a city/region could possibly exceed stellar job growth numbers. So we also need a strong trend of net positive migration. In addition, we need to talk to other REI's to try and understand market cycles (so we aren't buying in at the peak).
Metro areas are very useful in understanding all of the above on a regional level, without getting bogged down by RE-arbitrary city boundaries. So, in one example, buying in the right neighborhood would capture the stellar job growth and positive in-migration. That's why I feel the need to look at census blockgroups in metro areas.
Now, if all this sounds a little confusing - don't worry, the good news is that metro areas (by virtue of their multi-city nature) can support multiple job growth areas and multiple reasons for in-migration and, thus, the correct neighborhoods.
I'm working on a set of posts here, to my blog, to further explain all of this, and with some pretty cool maps too. I would love a follow and then some feedback from you.
Good luck!