At the same time the cash flow you already have effectively decreases the nest egg amount needed by an equivalent rate. 

We don't know your projected taxable income for 2021, your marginal tax bracket, the amount of the gain, the character of the gain, etc.You may pay some underpayment penalties if you don't pay in an estimate, you may not. 

And with depreciation (aprx 80% of $290k times 3.6%  ), ($8350 give or take) you have a taxable income of NEGATIVE $1100. 

With how long interest rates are right now, it is very unlikely that home prices are going to decrease.

Is there any way for me can have the government legally consider my situation where I can take business expenses to lower my personal taxable income?

-Demand hasn't decreased for housing.

Evictions decreased in 2020, eviction court has gone virtual, less evictions ruled against tenants, and speaks about rental assistance programs.Originally posted by @Will Fraser:Thanks for the thought, @Rob Bergeron!  

Our income has decreased for the last two years since we were traveling end of 2019 and early 2020 plus COVID shutdown.

Refinance is not a taxable event so it doesn't need to go back into the QOZF.

IRA will be taxable, and you would have to pay penalties for premature distributions.