Baltimore can be difficult to invest in if you don't know the area.

Hard money is expensive and makes it difficult to generate positive cashflow.

There are so many locals that are in need of a place to rent, but it is difficult to find anything.

It’s very difficult and with legislation currently being debated may become impossible to get a TVR (transient vacation rental) permit for single family homes, even if the home is somewhere that doesn’t have HOAs and would potentially allow for it.

somewhere difficult to reach, so they do not just arbitrarily reset your router because it has easy access?

I'm not sure how landlord friendly your state is, but some states make it extremely difficult to get a tenant out regardless of the situation. 

I just graduated this summer and I am having an incredibly difficult time finding work in the real estate industry.

From my desktop research looks like its quite expensive and difficult to earn an attractive CoC return.

Just be aware that cheaper properties tend to be:Old and require lots of ongoing repairs.Old and many repairs would cost more in order to bring the property up to codeTenants from on the lower end of income that tend to have more challenges paying the rentHigher vacancy and tenant turnover Higher frequency of evictionCheaper properties are more difficult to finance (for your future buyer) due to the higher cost of the loan relative to the loan amount.Price appreciation is minimalMany investors do not factor in the eROI (emotional ROI) which means such properties:Will create more "noise" in your lifeRequire more of your time and attention. 

Cash flowing in the area can be difficult, but definitely a possibility in C properties.