But, could the mix of strong inflation, increased unemployment, and all time high rents actually lead to a downward trend in D-B class multi-family rental values? 

Are you looking to BRRRR, househack, flip, buy and hold, or a mix? 

Of course tenant base and mix matter.

We know how the saying goes never mix "family and business" but if you do, establish who will be responsible for what, what is the exit strategy, what is the goal for each property, play out every thing that could go wrong and etc. 

Depends which area - for example, taxes are highly inflated in Key Biscayne so would have success there; mixed success in Little Havana.

Mostly C and D class cash flow rentals with a few commercial assets mixed in.

There is redevelopment, industrial to retail conversion, mixed use, residential, ground up, retail, spec building, land development, sub-division development, the list goes on and on.

We can also bring other people into the mix for more money but we want to avoid that as much as possible.

Seems like a massive mistake mixing up 2 transactions.

Thanks joe appreciate your delightful feedback.