My property is located in San Antonio.

And where is the property located?

After that, I would like to locate some properties that need to be fixed up and rents raised.

Needs some TLC, but is a great deal for a BRRRR.Tried to FHA loan it, but couldn't get around the fact that because of it's location near downtown, it is zoned as mixed-use commercial.

The Area: The town is Palestine Texas pop. 25,000ish the house is located in an older part of town but not in any danger zone.

We deploy 7 categories of criteria which each have a weighted value.

Also, your preference of location and condition may restrict your opportunities if you are too picky. 

I'm wondering how significant this is overall regarding resale, and whether I should adjust the MAO to be lower than 70% to accommodate the location--or expect a lower ROI at sale.

depends on location, in a city they should be within .5 mi, in a suburb 1 mile and rural  5 miles but unique properties can be stretched further, I have done thousands of BPO's for banks, the rules were 3 listed and 3 solds, within 20% speck and similar condition, and make appropriate adjustments for differences, there is more art than science to it.

It's a nice location and in good condition.