I have a SFR that is not set up for handicap access.   

Home Depot $99 for handicap height oval toilet.

Some markets handicap you from flips or cash flow type property, be willing to adapt to where you're at 

I have good credit and my monthly obligations on the student loans are minimal (so paying them month to month is not an issue)In particular I am more so thinking about potential cash out refinances and whether high student loan debt will handicap meThank you!

@Wendell Butler in theory yes, but its not a cut and dry eviction because the person is a relative to the sellers and handicapped.

The facility called and demanded I install a handicap ramp and rails for her.

You need at least certain sidewalk width for accessibility/handicap access. 

Given that they have lived in the unit for over 10 years and their mother lives there as well, this option may not work though because of the following RSO guideline:"If a tenant lives in an eligible unit but has continuously resided in the unit for at least ten years, and is either 62 years old or older, or is disabled as defined in Title 42 United States Code Section 423, or is handicapped as defined in Section 50072 of the California Health and Safety Code, the tenant is protected and the landlord cannot evict for an owner, relative, or resident manager move-in."

@Alex MondragonYour generic protected classes that you can't discriminate against are as follows. race, color, religion, sex/gender, national origin, and handicap. 

It gets ugly when they age out of the system, though, as the support for adults who have high needs is lower than for kids inside the system, and they usually end up in group homes or nursing homes, unless they are strictly suffering from a severe illness and have no developmental delay.But bank statements work, yes.I hope this is replying right....There are some families where mom is a stay-at-home special needs mom, and they often have like 4 kids who are severely disabled, and so it adds up to a decent income.But you're right, I'd expect them to own a home that's modified for handicapped accessibility.