I would like to offer the best "relational" way to handle this situation - which only supplements and doesn't substitute for Nathan's approach.First, have the persons you are buying property from notify tenants of change in ownership as soon as offer is accepted. 

I'm planning on using AirBnB/VRBO for the STR part, and probably use something like this for a longer version of STR to supplement the slow parts of the year with 30+ day stays for traveling nurses or other working professionals.  

To clarify, I understand that I may need to supplement my grandmother's bills with my own income, however from a financial perspective, my family gains more from preserving her funds than the the amount I would lose every month. 

The possibilities are endless and I personally believe becoming a realtor could be a good way to supplement my current income.

The bank I found that does mortgages as low as 30k tells me (a month into the process) that I can't use funds from my LOC or a gift to supplement the closing costs.

On our Supplemental Income report we are profitable as well.Will lenders be more interested in business income, supplemental income or would they treat them the same if they are both profitable?  

My 5-year goal is to supplement my (and my wife's) W2 with rental properties.

It's a great way for homeowners to supplement their mortgage payments/pay down their mortgages faster.(2.)

They could go into business for themselves (real estate or not), be my future business partners, or do real estate to supplement a W-2 job.

I am considering building a Supplemental Living Unit on my 10 acre property.