But the principles of commercial real estate apply to all segments.

In MC you can segment your list in all sorts of ways.

Whether you are going to mail to them or not, you can compare different segments/zip codes to one another in your market research.

If so, have you had any luck with using the map function to segment by street parameters within a zip?

List segmentation can occur at most any point, both in aggregating and compiling data records as well as during and after contact established during a campaign.In my early years we did not have the benefit of PC's, so we manually vetted records based on a cursory eyeball decision as to their likihood to produce a profitable result.

I've done pretty well in one segment of the stock market. 

It's too easy to just get lost in the pile.Two owner occupied segments have had success - without being over-popular yetSeniors with Long-Time Ownership15-20+ year ownership, age 60-89, specify median home values and eliminate known low equityOwners with Low Financial Stability Scores (FSS)Struggling financially, 5* year ownership, age 40-89, eliminate known low equity, and specify median home value.Your list broker can run reports for you and most will charge the same as the online systems like ListAbility or Listsource.

But the worst for me was during his closing segment. 

I suggest you use the mail > call > knock technique and build campaign(s) around a sequence of contact points after segmenting your lists. 

Three things you can do today to improve them...Segment your absentees...these are the most mailed lists of any (try mailing non homestead properties that may be listed as owner occupied) -I have bought a few last year from this.