Although it depends on location one thing that I have found is that in vacation and tourist areas many of the locals and individuals in the hospitality sector absolutely HATE Airbnb and other short term rentals. 

Fairbanks isn't nearly as busy as Anchorage or some of the tourist hotspots. 

Prices are better than in Galveston and even Port Aransas, but Crystal Beach doesn’t have the “other than the beach” tourist draw that Galveston and Port Aransas currently have.

However, it's close enough to the main tourist area that it has been quite successful. 

Investing in TODs near the Brightline station can be lucrative, as it would attract commuters, tourists, and residents seeking convenient access to the train service.3.

We're running similar numbers at our family residence, a 3300 sq ft Victorian in a beautiful, small, gold rush, tourist town in CA....walking distance to the historic downtown which enables us to rent out a tiny studio apartment on the first floor via Airbnb for 3-4 times the rate of a long term renter.Also, converted one of the master bedrooms with a private exterior entrance into another small studio by simply closing off an interior door, renting that out, too.Leaving our family with a high end, private 2500 sq ft house with 4 beds/2 ba, family room, dining, living, garage, etc.

A small town in a beautiful location, with an under priced real estate market, gets swamped by investors who bought up all the property to rent to tourists.

Tourist travel to the area.If the STR market remains strong it doesn't really matter what the broader market does. 

These counties have large areas which are zoned properly, and in fact have many communities which are purpose-built for vacation rentals which have hotel-like amenities which are in big demand with Disney tourists.

Cities with tourist attractions like Miami, FL, or Charleston, SC, might justify keeping an office space.