+1 To what Jared said. It really depends on your motivations and goals. Of all my neighbors within my close culdesac we have discussed this exact thing. Out of 5 of us, I was the only one to do a cash out refi to the max value I could pull out. All others either went to a lower rate in either a 15 year fixed from a 30 year fixed or kept a lower 30 year fixed. All of us agree that this year will be a great time to invest but each has their own goals and investment strategies as well as current financial status.
Being here on Biggerpockets, the assumption is that you want to build your real estate wealth so that would mean if you can leverage your personal residence to pull out equity, it makes sense. However, you do cite that you have concerns about future employment so that would be something to evaluate.
If you do a cash out refinance, keep in mind the market values might go down in the near term so it's best to do sooner than later of course mortgage rates crept back up with the flood of people refinancing the past month but is expected to go back down.