@George Fitz I can certainly see some potential up here (I live in Eureka, Humboldt County), but for slightly different reasons and in different patterns than most areas exhibit.
First of all, there is ample water here, one of the few areas in the state that has little to no worry about having a water shortage in the main residential areas. There is talk of some of the local water being diverted to the Central Valley, which should tell you just how much there is here to make such an effort worth the $$$.
Second, real estate here is VERY influenced by the marijuana growing. Ranches and rural properties are VASTLY overpriced, especially ones without any water rights, due to the ability to grow large amounts of marijuana to pay the mortgage. When full legalization hits the state, and marijuana prices drop, there is the potential for these properties in southern and eastern Humboldt to drop through the floor. Scenery-wise and outdoor opportunities-wise, these are amazing areas for a vacation, and probably vacation rentals, once the majority of the pot trade fades.
Third, there are a noticeable number of properties in the urban areas that would cashflow nicely. There is a fairly restricted number of units in the area, and rents aren't quite high enough to spur more development, so the right properties definitely have the potential to cashflow well at Section 8 levels of rents (even if you're not renting to Section 8). Nicer units don't command as much of a premium as they may in other places, but you can certainly get an extra $100-$200/mo if you allow pets locally, as almost no one does. If I was planning on staying in the area longer than I currently am, I would definitely pursue a couple.
Finally, while the county will never physically get closer to the Bay Area or Redding, and transit time from Redding isn't really improvable due to the terrain, there is ongoing efforts to make Humboldt more connected to the south. Current projects around Willits (in Mendocino) and southern Humboldt could cut travel time by 20-40 minutes when complete, making the drive up/down a bit less daunting. Opening up a secluded area like Humboldt a bit certainly has the potential to up property values as Bay Area folk look for places other than the Sierras for vacation homes or retirement homes.