Hi Jacob, a big part of my answers to your questions are covered by 3 things: strategy, financing, comfort level.
-Strategy: is your goal to conserve as much cash up front when purchasing a home or pay it off as much / as quickly as possible? Also are you looking to purchase a home so you can live for free or are you looking for long term appreciation?
-Financing: you can get different loans for different types of properties (unless you plan on cash). Here are some examples of low down payment loans, but investigate more please... Example 1: FHA can cover a single family home or up to a 2 unit home (I believe) with down payment around 3.5% to 5%. Example 2: first time homebuyer conventional loan for single family house allows 3% downpayment.
-Comfort level: do you and your spouse have a minimum level of comfort? Can you purchase a large single family and rent out the rooms while sharing common living areas like kitchen and bathrooms? Or would the requirement be that you have your own living space separate from tenants?
Use the BP calculator to run numbers and be conservative. Know the numbers and be real with them before jumping in on something and hoping it works... also balance this with knowing this is just your first house. There's a lot of learning in just going through the process for the first time.