Would you send a yellow letter to a large LLC?

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Lately, I've been driving for dollars and sending direct mail to owners of distressed and vacant looking properties. When I look up properties on a tax assessors website, I sometimes find that the property is owned by an LLC that owns a lot of other houses. By a lot I mean 20 or more houses. Some LLCs own 100+ properties. Is it worth my expense and time to mail to them? If the property is owned by an individual, or a very small LLC, then I always mail to them. I figure they will at least open my mail. I'm not sure about the big guys though. What would you do?