Selling a house hack and tax exemption

[John Carbone]

Does anyone know how a situation is handled where you have two structures on a property. Live in one structure for 2 years and always rent out the second structure. Then after two years rent out the structure being owner occupied for a year. 

If the property then gets sold do you get to pay no taxes on the sale of a primary residence since it was occupied 2 of the last 5 years? 

I’m wondering what the most optimal way to do this if there is a huge gain on the sale of the property of up to 500k (filing married)

I’m not asking for official tax advice, I do have an accountant I will finalize this with but I do like hearing other peoples opinions who have done similar.