Mini splits, filters? Mold?

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Hi, I am wanting to hear if anyone has had problems with mold in their mini splits? 

I’ve got to put in new hvac and two hvac guys suggested I use mini splits. 

I have been looking them up and seeing that some filter needs to be replaced every two weeks, and they are likely to get moldy. 

Pittsburgh, where this duplex is at, has high humidity. I can’t imagine what the headache could be in getting these installed in the long run. 

Does anyone in this part of the country where the humidity and temperature is high, have these mini splits? And do they cause a headache? And do you change the filter every two weeks!?

I have central heat and air in my residence and run into no problems. 

I have an air purifier that requires new filters every six months and I’m never on it enough to comply. And that’s every six months not two weeks?!s

Sheesh