Should you sell your problem property--even at a loss?

[Larry Turowski]

Brandon Turner asked a question about what "problem properties" would you never want to buy, here.

Yet many of us HAVE bought what turned out to be problem properties.  I bought a duplex in a D neighborhood that cash flowed really well but was too much of a headache and too much stress for me.  I dumped it before I could break even on it--and couldn't be happier.

It seems nearly every podcast Brandon mentions this one particular property that he is underwater on, doesn't cash flow at the minimum of 1% of the cost, and has problem tenants.  Should he sell it?

Problem properties are not worth the hassle to me.  I'd rather cut my loses, count them the cost of education, and move on.  How about you?