negotiating an "as is" home

[Ryan Deeter]

is it ok to negotiate an "as is" home in a competitive market?   I am in contract with a duplex that needs maybe 10K more than I expected.  Should I see if the seller is willing to negotiate on the price? They have already been in contract once that feel though due to financing of buyer.   There are also no current renters as they moved out anticipating the the sell of the home with the first potential buyer.  

Thank you for your help.