Is a 3BR 2Ba a better rental than a 4BR 2.5 Bath ?

[Navtej Singh Saini]

I am looking to close on a 2300 sqft 4BR, 2.5Ba really nice house in Fishers, Indiana. It has a big yard (0.25 acres). This is my first ever buy. The plan is to live for a year and then rent the place out to a family. My concerns are the following:
1) Will it be difficult renting the house that is a 4BR house versus a 3 BR house ? 
2) I am concerned about being able to manage a big preoperty as a landlord. Can anyone who has done this offer some insights and tips?