Also, @Zeona McIntyre and @Sarah Weaver's book "30-Day Stay: A Real Estate Investor's Guide to Mastering the Medium-Term Rental" was tremendously helpful; the bonus chapter by @Jesse Vasquez led to helpful advice from him on BP Forums.

Another bonus is if they are actively house hacking themselves or doing some form of RE investing.

Hopefully it is more of a bonus for the room that has it like my tenants see it as in the units that have it.

If I decide to take on any work myself then its just a bonus. 

We plan on starting with the bonus room of our current SFH then purchasing another SFH in the next 6 months with 5-6 beds to continue this strategy.What are the biggest considerations would you take with renting by room?

Simultaneously, I'm looking to get into a larger multifamily (between 6-12ish units) in Kansas City, MO to build up equity faster and get some cash flow as a bonus.

I generally reinvest the proceeds from these businesses, but if I wanted to take some out for living expenses, I'd probably just structure it as a salary or bonus taken from these entities and passed onto me (I have a 'day job', so I don't depend on this money for my living expenses).  

You likely need to capitalize the costs since the property appears that it was not 'in service' yet.Therefore, some items would be slowly depreciated and some items would be eligible for bonus depreciation.

If the tenant leaves and there's no damage I get a bonus.  

Lucas Burrington, the owner, also provides leads on investment opportunities every once in a while so that's a bonus!