You can probably pay the same or less than what you're paying in Astoria if you house-hack a duplex.The only way I'd suggest a SFR as a first investment is if it has a live-in basement that you'd be willing to live in short-term.As far as location, its best to first get an idea of what you're qualified to purchase.

I'm pretty sure that Zeona McIntyre (BP Podcast ep. 229, https://www.zeonamcintyre.com/) will manage properties regardless of location.

A basement may be used for habitable rooms or a dwelling unit, regardless of the depth of the floor below grade, if the floors and walls are impervious to leakage of underground and surface water and are protected from dampness, and if the required minimum window area is located entirely above the finished elevation of the grade adjoining the basement wall in which the windows are located.

It's all about location.

Are you located in the Kansas City area?

I have been interested in buy and hold properties for some time now, but have been reluctant due to the feeling of not being in a stable location. 

Did you ever locate one?

This is similar(ish) to trying to predict gentrification trends with new Starbucks locations.

As I said numbers do not tell the whole story we need more info on the property and location to make an informed decision. 

They've set guidelines for their comfort levels on things like:  Location, Property type - SFH, Multi-family, Apartment complex, commercial, other - etc.