She mentioned she wanted to get rid of properties and that tenants are difficult to deal with.

If not, then there is your price - with perhaps a small adjustment to account for market appreciation over the past 18-months.If you have done alright by this property (& the tenant) and are ready to be rid of the property, then your choice is are you able/willing to sell it for $375 - $380K or do you wish to wring everything you can from your tenant?

And get rid of a problem house. 

Be understanding, give them proper notices of the new rules, be patient a little bit regarding the  new rental rates, what is expected of them, and then if they think your rules stink, they'll move, or then you will have to get rid of them. 

Would they want you to get rid of the tenant (most leases have a stipulation that criminal activity is breach of lease) and that you would, if they'd stay.

The property sold for $72,000 in 2007 to the current owner who is looking to get rid of it.The seller is motivated, although he hasn't said why - just personal reasons, and said he is open to seller financing.  

First thing first, I need to get rid of my debts. 

The lady owns two homes and states she wants to get rid of both due to purchasing a new home.

Homes selling on the high end for the region.The owner wants to get rid of the property because he's let his sister live there who is married to a violent criminal with 17 assaults on his record. 

Since he is a motivated seller, he may just want to get rid of the property quickly...