So my wife and I have been fortunate financially through hard work and lots of schooling. Long story, as short as possible, we are mid 30s with $600,000 retirement/investment portfolio. We max out 401ks and backdoor R...

This is definitely where we'll most likely see an impact on the RE industry.

This does not impact their appetite for loans that are granted to you and I directly from the agencies. 

We are not planning on permanantly occupying  the property until retirement in a couple of years, but do want to use it occassionally when time allows. 

Going to call an exterminator to take care of the mouse but also want to permanently stop future occurances. 

Weather impacts house shopping, traveling ( spring break) keeps people away from house shopping, etc.

If it is decent and inhabitable, your lender should be able to finance it If it is not inhabitable, then you could get a construction loan through your lender to bring the property up-to-speed and then refinance into a permanent loan once it's done.

The greatest impact that low rent did was delay the time to profitability on this property for quite a while. 

And the great thing is, servicing doesn't see your names attached to the loan, therefore allowing you to take out as many loans as you'd like with little impact to credit..

That will help you think about how market issues like interest rates will impact your goals.