Even if one tenant is responsible for rent payments, the others will live there and impact your liability as a landlord.Accountability:Requiring all adults to apply and sign the lease holds everyone legally responsible for the terms.

Live in one unit - It's a great strategy when using a bank for financing as the down payment and interest rates are more favorable to owner occupants.  

I tried to work with the tenant but they have stopped responding and refuse to pay rent anymore, I don't even know who lives in the unit anymore.

If your medical condition qualifies as a disability and your current living situation isn't suitable, you might have grounds to break your lease without penalty.'

There just trying to eek out a living too.

Quote from @Kristi Kandel: Helping LA Communities Rebuild After WildfiresWhen Hurricane Ian hit Fort Myers Beach in 2022, it changed our lives forever.

Smaller SFH = less maintenance , there are lots of single looking for a place to live .

Where I live, we still have a severe shortage of homes--median time on market is still 7 days and it would likely be shorter if not for delayed negations being the norm. 

He would need to find a place to live,which would take money off the table for collateral in his next deal.

Live way below your means and save the majority of your income.