In this instance, I'm using portfolio to describe a non-agency loan.Depending on credit score, you should be able to find a portfolio lender that will go to 75% ltv with no seasoning.  

Typically we have gone conventional financing for our primary however that does affect our DTI when we are trying to get into commercial and building our rental portfolio this year we want to keep our DTI down and our credit score up as well as as much available liquidity as possible.Any suggestions on how to analyze the numbers for a primary, what would be the MAO if holding for 5 years then sell.  

We also all have good jobs and great credit scores.

I may have missed a detail here or there, but this is a pretty solid version of how it's done in my area. 

Also, your credit score may be higher than @Richard Moreno's. 

My wife got into the military and has now graduated Basic Training and is now doing AIT school training she is receiving a bonus of $25,000 $10,000 in cash when she finish AIT school in May and we both have good credit scores mine is about to go up over 700 hers is in the Mid 600 range.

Doesn't it negatively impact my credit score every time I ask a different bank if they can prequalify me?

My question is does anyone know if accepting the HELOC, but not accessing it yet, will affect our credit scores and make it more challenging to qualify for traditional mortgages.

Short-short version: I'm curious about buying a small multi-family to house hack.

They will look at you for credit score and criminal background but for the most part it's based upon the properties ability to generate enough profit (NOI) to service the debt (principal and interest).