Theres no value difference in the 2 sizes mentioned.

However, if you fall into $1M-$1.2M loan amount (which I will) they can still deny based upon loan size or simply give you the underwrite from hell.

The ARV of a rehabbed property, almost regardless of size and location, will be over $200k.

Perhaps you only need to create a few more chart of accounts, charge, and expense etc categories?

Looking for somebody to set up chart of accounts, items, show me how to record a purchase and sale of property, etc. 

SFR is a light switch either on or off, medium sized multi family is like a dimmer switch there’s always some light.  

@Lily Nelson generally if you are priced right and listed on the major rental sites in a city of decent size you shouldn't have a problem, keeping tenants has a lot to do with the quality of the unit but some things are beyond your control, responsible tenants eventually buy homes in most places. 

For example, when we found our house, I ran searches on AirBNB and VRBO/HomeAway checking on places that had similar size, features etc.

For example if you have a mom and pop tenant based on 17 bucks a foot rent because that is all their business model can support but a national tenant wants the site and can pay 22 because of location not only can rent potentially increase but also that new tenant value can be a massive difference.Mom and pop at 17 a foot and an 8 cap for instance.Say 4,000 sq ft box X 17 = 68,000   (8 cap) = 850,000National tenant at 22 a foot. 4,000 X 22  = 88,000  (6 cap) = about 1,470,000There are expenses involved getting the new tenant but value difference can be massive.Leasing brokers can perform a (void analysis) which not only looks at rent comps for box size but also what existing tenants are in the market,saturation levels, and what possible tenants optimally could go in that space.    

I don't know the answer but I would bet Las Vegas in general is has a low stock of 4plexes relative to other cities of our size.