The areas surrounding the majority of the major high rises are depressed and have lower home values.

If an applicant tells you they have three cats to help with their depression, that's not allowed and you can reject them.

Mostly because I don't have solid steady proof of income yet from my business.There are a few depressed areas (Anderson/Muncie) around Indy that I've looked into and they're super cheap (10-20k max but needs moderate rehab).

And further back in the Depression the govmit set up CC camps .. put people work paid them .. it was hard work that I am afraid the majority of our population probably cant or wont do..   

It is a Depression-Era, 1930 single family home with Art Deco design elements located about a block from the city's rejuvenated downtown area, where there are shops and restaurants, and across the street from The Siloam Springs Museum.

If you started studying since the change in the millenium, the last major depression was a mortgage crisis literally derived from this.One "catch" that people don't understand is the difference between who owns the Note/loan and who does the servicing. 

I was struggling with depression, anxiety, and undiagnosed ADHD.

Every since the last depression, mortgage lenders have taken over and the deposit banks are only originating something like a third of what they used I believe is the statistic.As far as loan products, yes your "average" lender may not do well for you if you want a new construction loan... 

I bought them because it was a depressed market and I was buying them CASH and they would cashflow well.

In those days, the neighborhood was depressed and high crime.