Cathedral ceilings/windows, tongue and groove walls, etc.

Your air ducts and ceiling fans will be full of lint.  

I had to deal with a lot more issues than I've ever had in non-S8 rentals like extensive property damage and also bed bugs, roaches, drain lines completely clogged up by grease (I learned what sewer worms are, look it up), spray paint art on walls and food on ceilings, noise complaints, police at the property, removing dead bodies, etc.  4.

Completing cosmetic updates to the interior, painting the whole interior, removing drop ceilings to make the space feel bigger, gutting and renovating one of the bathrooms.

Fines, theft, fires, drug overdoses, collapse ceilings it never stopped.

Coped ceiling added some cost.  

A few weeks after painting, light brown marks appeared at the top of some of the top corners of a few of the walls on both sides of the house, upstairs and downstairs (not the ceilings, just the tops of the walls). 

I bought a flip because none of my clients wanted it on 832 White Street...I know some of you know that street and it's right near Lee St -- huge flat lot, 2500 sq ft, 3/2.5, I had never seen true 14' ceilings in a 1920 built home....I mean wow, but it was still, eh

I was in a situation similar to yours and I have a duplex corner unit with a natural basement egress and tall enough ceilings.

For example, if mold was found in the master bathroom ceiling in an occupied home a protocol in that scenario may call for a pack out of the entire master bathroom and bedroom everything within those two rooms would need to be cleaned off-site and then brought back.