If you like the urban culture then maybe downtownIf you like young party scenes then maybe PB and MBIf you like upper class then Rancho Santa Fey, La Jolla, CoronadoIf you like liberal (think Berkeley) then OB, Hillcrest, north park   If you like rural city in county feel with great community think Poway or BonitaIf you like casual upper class but not super upper class beach then Encinitas, Carlsbad, del MarI live in Poway and love it but I may retire to Encinitas by Moonlight Bay.In summary you are the only one that can determine best area for you.  

Texas is the fastest growing state, so we are getting more than our fair share of new people, couple that with properties that are still reasonably priced (except Austin), with exceptionally low interest rates, and lastly a culture where duplexes communities thrive and are plentiful to invest in.  

I am interested in the rental culture in Cleveland as this is the type of neighborhood that I have never invested in.

However, I think you are underestimating the cultural shift in America.

On the commercial side, two things to keep in mind are the culture and the community that the office creates.

Along the way, I am also looking to develop a network of professionals to be able to grow with and share ideas.The family and I love the Triangle area for the balance of work, play, nature, culture, sports, and the overall warmth of the community. 

I'm liking Irish Hill north of Fountain Square, Bates Hendricks, and the old Southside.

I moved about four years from Fort Lauderdale to Birmingham, AL ( culture shock).

We're considered a noteworthy city mainly because of the cultural and historical relevancy of the area.

For other folks out there who may have never moved from their home town and are raring this thread it may be useful to keep in mind.My vote is for Tampa.Vibrant downtown, great university, cosmo city with its own rich history and culture and beautiful beaches.