Around 2008 they changed the rules where it just became two kids per bedroom(they call it two heart beats per bedroom on the street-weird I know) no matter the gender.  

Nope because antifa is not a protected class.Here are the protected classes, for which, we as a democratic society, have decided to protect:RaceColorReligion or creedNational origin or ancestrySex (including gender, pregnancy, sexual orientation, and gender identity)AgePhysical or mental disabilityVeteran status

In the last Congress, a bill (H.R. 6500) was introduced by Representative Jerry Nadler (D-NY) to amend the Fair Housing Act to prohibit discrimination on the basis of sexual orientation, gender identity, source of income or marital status.

A couple of things to consider, when analyzing applicants, do not look at name, gender, familial status, or any other inane criteria. 

I have the following blurb (for this exact same issue) as an addenda item in my lease that was also acknowledged and signed by them;"Resident acknowledges and agrees that this is a co-ed (mixed gender) and co-living house. 

Though as others noted, kids, gender, etc... is off the table for rental advertising.  

AirBnB doesn't give up the gender of the hosts, you need to guess at it from the name.

Historically, when renting on a per room basis have you mixed male and female tenants or do you try to keep a property all one gender?

I wont engage with someone who decides to identify people by color, gender, and "white trash".

Honesty, it will drills down to region culture and personality preference (lot of other factors that I bucket under personality such as age, gender, etc).