Unsure about STR regulations in Charleston but I would advise you to search "arbitrage" on this forum and read up on the hundreds of pros and cons responses here before diving in to any market using the arbitrage model.

Also, our team has a lot of experience in working with Sec 8 residents and getting properties approved.

Check out the different Forum Categories here as they can answer a lot of questions you have just reading through.

And in order to defer all tax you must purchase at least as much as the aggregate net sales price of your properties.These all can seem daunting but in my experience exchanges are more successful than not.

Lots of folks invest here. 15+ years Realtor/Wholesaler experience.

I have experience with minor to medium size rehabs but nothing as extensive as needed here.

The unique thing about this platform is that you can actually search reviews from BP members and interact with them about their experience with that particular QI.

In my experience Vrbo has buried Airbnb. 

If so, how was the experience ? 

I would recommend talking to many lenders/brokers to see which one has the most experience funding these loan types.