Since we cannot predict the future, and you said you want to be safe with your money it sounds like;  I would personally not invest based on speculative appreciation, but that's just me and to each their own

I would like to receive some advice regarding the following:1) what are the potential markets that are the best to invest in for multi family, duplex, triplex and fourplex (preferably outside the Golden Horseshoe area as I don’t want to deal with the speculation tax).

If you're okay with that and want to play the appreciation game, then I can understand that but it's all speculative investing at that point.

In the last few years we flipped a few houses (major renos) but not EVERYTHING is overpriced and any play is based on future price speculations.

[I am still a newbie and haven't bought any properties yet so this is speculation but this feels like a reasonable explanation.]

Bernie Sanders wants a 25% “house flipping” tax levied against investors who sell a property at a profit within five years of purchase.He also wants a 2 percent “empty homes tax” on the property value of vacant homes in order to discourage real estate investment.From Bernie's Website"When Bernie is president, he will:Create an office within the Department of Housing and Urban Development to coordinate and work with states and municipalities to strengthen rent control and tenant protections, implement fair and inclusive zoning ordinances, streamline review processes and direct funding where these changes are made.This office will convene key leaders, academics, experts, local officials, renters, tenants, and homeowners to create and implement these necessary solutions.Preempt laws that prevent inclusionary zoning for luxury developments.End exclusionary and restrictive zoning ordinances and replace them with zoning that encourages racial, economic, and disability integration that makes housing more affordable.Require that recipients of federal funding from the Department of Transportation and the Department of Housing and Urban Development make these important zoning reforms.Provide funding to states that preempt local exclusionary zoning ordinances to make housing more equitable, accessible and affordable for all.Make federal funding contingent on creating livable communities.Encourage zoning and development that promotes integration and access to public transportation to reduce commuting time, congestion and long car commutes.Prioritize projects that reduce greenhouse gas emissions, create walkable and livable communities, and reduce urban sprawl.Encourage zoning and development designed to expand and maximize the number of units fully accessible to people with disabilities.Place a 25 percent House Flipping tax on speculators who sell a non-owner-occupied property, if sold for more than it was purchased within 5 years of purchase.Impose a 2 percent Empty Homes tax on the property value of vacant, owned homes to bring more units into the market and curb the use of housing as speculative investment.Encourage “circuit breakers” on property taxes to protect homeowners in gentrifying neighborhoods from being priced out of their own homes as their property values rise.READ MORE: https://berniesanders.com/issues/housing-all/From my point of view, anything that impedes or obstructs REI's cash flow is a bad thing.

It's more common for their policies to discourage RE speculation rather than encourage it.  

The annualized return is highly speculative, so you can really only use CoC for an apples to apples against stocks.

I can see with my own eyes certain areas improving, demographics shifting, and speculate with confidence when it comes to value-adds.

This is actually my long term goal here in town, but my cash position won't allow it just yet, and it's too speculative for me to want to use OPM.