I suspect Detroit could be ripe for this as lots I bet are basically free..

It's tough to say with certainty and it a lot of success in the MTR market hinges upon operating ability, property layout, understanding your clientele and ability to adjust to the market.This article does flag some cities that are good for MTRs: https://www.stessa.com/blog/hot-spots-medium-term-rentals/

Best bet would be to call up the Zoning Department and ask. 

@Hitanshu Shah-congrats...assuming the 4 plex will be a rental - your best bet will be 25% down and likely a 30 yr fixed program ....if you plan to sell or refinance  the loan within a few yrs - focus on the option  with the lowest loan fees 

I bet jurisdiction architect is more qualified to determine requirements.  

You bet!

@Leah Smith DSCR that allows STR income is likely your best bet.

You best bet for duplexes are going to be East Dallas and North Oak Cliff.

The only way it would make sense to have little cashflow is if the location is PRIME and you are betting on appreciation over the next 5 years. 

But take actionable progress in the area's you identified you want to bet on.5) Have some conviction the direction your going, #1 will save you from some mistakes.