As a tenant, if the restaurant has music and/or sells alcohol, it can be a problem. 

During the term of the lease (the initial term of the lease or any extension term), the owner may only terminate the tenancy because of: (1) Serious or repeated violation of the lease; (2) Violation of Federal, State, or local law that imposes obligations on the tenant in connection with the occupancy or use of the unit and the premises; (3) Criminal activity or alcohol abuse (as provided in paragraph c); or (4) Other good cause (as provided in paragraph d).

I have sprayed the White Shellac version and it needs denatured alcohol for clean up.  

I have seen food sent home with kids only to have the parents sell it for drugs or alcohol.

The boyfriend of her's might have sold it for their drugs and alcohol.  

Further, an opened notice from the DMV in this tenant's name related to driving under the influence of alcohol was on the floor, and an unsecured Smith and Wesson handgun was sitting on the bedside table.

In Michigan, you can insert this clause in your Lease:ILLEGAL DRUG USE: Tenant must not violate, or knowingly allow another to violate, federal, state, or local laws regarding the use of controlled substances or the use of alcohol by minors in or around the premises. 

We draw the line on storing liquids such as {lamp} alcohol, kerosene or gasoline in the living space {if there is a garage and the liquids are properly stored in approved containers, that is fine}.If you are signing a single lease with the group of tenants you can require they furnish you with have proof of renters insurance and that you are a named insured on the policy ... you can also require their consent for you to contact the insurance provided to verify coverage.Let them work out whether they purchase individual policies or a collective policy - there's a good chance they will not be able to purchase a collective policy - or that it would be cost effective. 

You may be able to put limits on the total number of humans allowed in the unit, credit scores above X for each adult, no rude people, people who smell like alcohol at 10AM, smokers, leather-wearers, vegans, etc.  

People who have this addiction are more likely to gravitate toward other addictive substances too, like drugs and alcohol.