I became an accidental landlord in Portland a few years ago when I decided to move out of my SFH and rent it out. It's been a good experience, so I decided to buy something else--a SFH in a hot neighborhood that I plan to convert to an owner-occupied duplex. Sale is now pending.
Being a newbie to real estate investing, I was trying to pay attention to what people on BP and elsewhere were saying about cash flow, the 1% and 2% rule, etc. It seems hard if not impossible to make these rules work in Portland unless you know how to buy houses for much less than retail, which I don't. And in any case, when I asked an experienced investor in Portland who rents out higher-end houses in the $2500/month range how he dealt with vacancies, he just gave me a blank look. He doesn't have vacancies. That's Portland for you. (Or, to be more accurate, that's Portland when you have a great house in a great location.)
I won't have much cash flow until the loans for the duplex conversion are paid off, but I think it's a great investment for the long term. I lack expertise in RE investing, but I do know my city quite well. That's worth something!