@Hani Alomar
That's a pretty loaded question. There are strategies for every market phase that allow someone to invest and succeed in any market.
The reason a lot of people are investing in the midwest now is cheaper property, and higher cash flow than they can find in major markets that have appreciated heavily- like CA. Another reason is lower volatility- select midwestern markets don't appreciate or depreciate as much as the aforementioned major hubs. This means that, compared to more volatile markets, if you buy them at the bottom you won't get a lot of appreciation, and if you buy them at the top you won't get a lot of depreciation.
The depreciation buffer doesn't matter so much though, because your goal is to hold this for it's cash flow and not sell it at the bottom. I would add that in working class midwestern neighborhoods, rental demand doesn't generally change a ton during recessions because of the blue collar nature of the subsection of the economy that you're investing in. SO, you should cash flow pretty similarly as you would today if you were to endure a recession with this property in your portfolio. If you were to sell it, you would ideally sell it during a favorable economy, and you wouldn't necessarily expect a profit from the sale. Your focus would be rental income.
That last statement is really important. You're not going to cash flow in expensive markets, and you're probably not going to see significant appreciation until the next market peak... so no point in buying in those expensive markets until we're in a bit of a trough. However, that doesn't mean ANY midwestern market is a winner.
If you're going to invest in the midwest, the rental income has to be substantial enough to account for the fact that you're not expecting much long term appreciation. Remember, you're buying high regardless of the market. Don't go invest in some major midwestern city that's been flooded with CA investors for the last 5 years. You're NOT going to get a winning cash flow deal this way. If someone tries to promise you appreciation in one of these sexier midwestern cities in order to compensate for lower cash flow... remember that appreciation is not a part of your strategy right now.
***I generally recommend seeking out C+/B- rental properties with a 10% cap rate, or a 20%+ cash on cash return with financing*** You will probably find this in secondary markets. Not all secondary markets are good though- look for markets that have sale prices of a smaller city and rents comparable to big cities nearby. Seek out high rental demand, low taxes, low city water/sewer bills (you could end up paying this if you buy small MFR) and landlord friendly laws.
These markets are hard to find. They're hard to find because fewer investors are on BP talking about them, which in itself is part of the reason they still offer some of the returns that they do.
Don't be fooled by the popular, big, OOS investor midwestern cities that everyone here started talking about in 2013 as soon as CA prices took off again. Our peers have been mining those markets hard for 6 years. Google "blue ocean theory".
I hope this long and drawn out post helps you and everyone else on this thread!