If you are looking for speculative appreciation, the larger cities are good possible investments, however, the prices have already risen significantly so it is very hard to find good deals.
Smaller towns and cities that haven't yet returned to their 2008 prices are where I recommend people to invest. For example I am selling a furnished 2br/1br duplex for $100k and will carry the first at 9% interest with 30% down for 3 years to give you time to refinance and get your own 30 year financing. If you are creditworthy, get your own loan and take a 10% discount off the sales price. Here's the numbers...
Income via AirBnB or Traveling Doctors/Nurses income is approximately $2,400/mo. ($28,800) Owner pays all utilities/landscape expenses. Gross Rent Multiplier 3.5!!! Allow 20% vacancy $5,760 equals $23,040 annual income.
Income via annual leasing is approximately $1,500/mo tenants pay own electric/propane. If interested, PM me for the breakdown.
Buyer Conventional Loan: $20% down $72k = $382.51 mortgage pmt @ 5% 30 yrs
$383 Loan Pmt ~ Seller Financing $525/mo ($70k loan, $30k DP still plenty of cash flow)
$65 Insurance
$50 Lawn/snow removal
$180 Property Taxes
$250 Utilities
$60 Misc
AirBnB you would charge a cleaning fee so that is not a expense to bottom line
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$988/mo NOI Conventional Loan
$11,856 Annual NOI
$18,000 Cash Down plus $3k closing costs. Almost a 50% ROI Year ONE!
This property sits on a 1/4 lot with a year around brook along the rear property line. It is NOT in a flood plane zone. Fully furnished and renovated including new roof, recent F/A furnace, window air conditioner. All work done to code and with permit.