Hi Shelby,
Just my thoughts, here are a couple things I would consider right off the bat:
*I'm assuming the interior of the house has also been adjusted to accommodate a handicap? If the house has already undergone expensive and intensive changes, it may be worth it to keep it and see if you get any bites the way it is. On the flip side, if it's really only a few changes they made in the interior to accommodate a handicap, it could be better to reverse those changes, just the major ones, as handrails and smaller adjustments are great safety features for anyone.
*Where is this located? If this house is in a more densely populated city you may have a better shot at finding tenants. On the flip side, if it is less dense, I would reverse the changes and increase your chances of finding tenants.
*Take a look at what is currently available for rent in that area. Are there many places available? Are there few? Any handicap? This may be a niche property OR you may be in a competitive market where you need to make the apartment as available as possible.
*Lastly, consider your financial situation. Do you need to get this rented out or you'll be tight financially? Or can you afford to leave a For Rent sign out for some time while you gauge the market for a handicap friendly property?
Hope this helps in any way. Good luck!