MTR and Section 8 are very different niches with little in common so it's very difficult to provide advice on your question. For example:
- Section 8 properties are usually in rougher areas. These do not make good sites for MTRs.
- Section 8 properties will be unfurnished. MTRs are always furnished.
- MTR guests expect a hospitality experience, much like STR. This is not the case with LTR or Section 8 tenants.
- While self-managing either type of property is possible, if you hire out property management you'll pay a higher percentage for a skilled MTR manager than for someone to manage your Section 8 property.
- While MTRs can be any size property, the bedroom/bathroom count is really important, especially with larger properties. With Section 8, pricing is based on bedroom count only. It's not unusual to see 3/1 and 4/1 Section 8 properties but that single bathroom would not do well as an MTR.
Overall, I'd say location and the shape of the property is going to be your key driver and the factors that will make or break you in the MTR space so very carefully evaluate both before you make your decision.