@Gary Hall it looks like my post came out far harsher than I intended. Nothing personal was meant towards you or anyone else. Clearly everybody has the right to set their criteria wherever they feel comfortable. It's your asset and you have complete control (unless local laws mandate other things).
I would also say that in the Denver area, if you aren't getting a large number of applications, then your pricing is possibly too high for the neighborhood, but always pick the strongest applicant.
I will stick with what I meant as the main point of my post. Having been a wholesale AE for a mortgage company for many years and working in about 35 states, I will say that while the ratio of income to rent/mortgage is certainly important, in high cost areas we would grant a great deal of flexibility to those who had a significant amount (based on actual dollar amount rather than a percentage basis) of disposable income. For instance we would often allow borrowers to go to 55-60%DTI if they also had disposable income, after all expenses, of $3,000-$4000 per month or higher. To us, this meant they had a decent amount of discretionary income they could allocate towards rent if something else went wrong in life. It was huge in terms of "compensating factors".
Of course that level of disposable income was far more common in high cost living areas like LA, San Diego or Seattle than it was in Wichita KS. Nothing against Wichita or other areas. It's just a demographic thing. But it's also why higher priced cars tend to be more prevalent in those types of areas. A higher percentage of the people there make higher salaries. A car payment that would be a huge percentage of the average persons salary in Paducah Kentucky, would be a relatively small percentage in Boston etc.
Again, whatever makes you comfortable in renting your asset out is what you should do. I was just trying to say (again, I do apologize for the tone) that strict percentages that may be appropriate in one market don't always make sense in another market.