Hi Matt-
My "expertise" resides only in single family homes, since that is what I have. I can tell you there are a lot of good posts about this topic that will help bring to light some questions you may not have thought about. I certainly found that out when searching about the same topic!
Pertaining to your question, it all depends on what you want to get out of your investing. As for single family, here is some feedback based on my experience from my property.
*Longer tenant occupancy (mine is on their 3rd year)
*Tenant is responsible for lawn/snow removal
*Tenant treats a SFH as a home, and generally takes better care of it
*financing can be easier
*Broader pool of buyers when planning your exit strategy (First time home buyers, investors, corp housing, etc)
*overall less maintenance (Depends on condition but less units to repair during turnover)
*less taxes (Depending on area)
*tenant pays all utilities (Water, gas, electric)
These are just some things to think about, and based on what my SFH does. I hope this helps shed some more light for you and helps you figure out more clearly, what your goals are, and what sounds better suited to your style. I know by reading others posts, it helped me shift priority from multi- BACK to SFH. That said, both SFH and Multi have pros and cons. Good luck!