Hi @Steven Brown, it really comes down to a few different factors.
1. How long do you need the money for? Most HELOCs are ARMs so with the rising rates, if you plan to pay back the money within a year, it is likely the better option. However, if you are tying up the money for an extended period of time, I would go with a cash-out.
2. How much equity do you have in your home? You need more than 20% equity to do a cash-out but some HELOCs can go up to 90% LTV.
3. Predictability. If you value stable and predictable payments, a cash-out may be right for you. HELOCs are generally easier to get in over your head with so if you have issues with that, a cash-out may be better. If you are known to be financially responsible and can handle the risk of changing payments, the HELOC may be a better option.
I just realized that I used a lot of acronyms so if you have any questions please let me know. Hope this helps! Let me know if I can be of any assistance.