@Chad Gardner - this is one of the most common questions we get from potential/future househackers.
It's hard to speak in such broad terms - one man's "cashflow" is another man's vacancy reserve, so whether you can pull it off or not will be somewhat determined by how optimistic you're willing to be. If you are pessimistic you'll certainly not see any cashflow. Better than each of those options is to be realistic, what most of us aim to do, but easier said than done.
Even without a budget for repairs/etc - let's just define "cashflow" as income left over after PITI & utilities for a moment - Mac Groveland and Highland Park are going to be tough. Solid 2-4 unit properties are so scarce in these areas (~21 sales in last 12 mo between the 2), the market simply doesn't allow a buyer with a low downpayment to enjoy any "income" out of the gate. This isn't so much due to interest rates - these neighborhoods have been this way for at least 4 years. Demand was much higher when rates were lower - you might be able to scoop a solid 1920s Highland up/down duplex for 10% under list and 20% less than it might have sold in 2021 - but current rates erase any potential savings. I would personally rather be the guy with the lower purchase price and higher rate, but it doesn't help a brand new househacker in the short term.
There are 2 ways to pull it off in Highland/Mac/Cathedral Hill/Summit Hill - 1. Go Big (4plex, spend 700k +) or 2. Buy Something Ugly. You'll need patience as these opportunities don't come often, but it can be done.
"South Minneapolis" is such a broad term - there might be as many as 25 different neighborhoods ranging from A-D class, each with their own pros and cons. If I'm looking to househack with my family (I had a toddler and a newborn the last time we did it) I might be interested in 1/3 of these neighborhoods, of which a few will absolutely produce some income (assuming you're number's aren't ultra-conservative) upon moving in year 2-3. Too much to discuss for a BP forum, but it can be done.
The good news - there are plenty of family-friendly neighborhoods between St Paul and S Mpls which offer decent opportunities for a househacker - you just need to know where to look, what to avoid, and where the opportunities are (undervalued properties, under rented units, value-add opportunities). To be clear - you aren't wrong, it's harder right now. I might have sold 20-30 solid househacks to new investors per year between 2020-2023 - this year I'm doing less than half that. All that means is you need more patience - and if you're looking for a summer move and making a gameplan in December you'll be just fine.