Prospect follow up when being ignored

[Ashton Karp]

I am finishing my first year as a real estate agent and am hitting a block with follow ups on leads. I focus my business on door knocking, cold calling, and my sphere, with the intent of purchasing physically distressed property when I am in a stronger capital position. 
The amount of qualified leads that I am coming across is fairly high but I am having trouble getting responses from a lot of them. I will verify the correct contact information so I know I am reaching out to the correct individuals and I will even have responses that show interest in selling or purchasing. A lot of these leads go ghost after one or two interactions, if they respond at all.
When this happens what is the general response I should have? Should I continue to reach out regularly in different ways (email, phone, knock on their door, etc.), leave them alone, refer to someone else or other? 
When I do reach out my touches range from “just checking in” to applicable market updates or explaining I only need a few minutes of their time to discuss XYZ. 
Any help or advice in regards to these situations would be helpful. I can provide specific examples of prospects if needed to clarify my situation.

Thank you!