bedroom upstairs and toilet only downstairs. is this an issue?

[Chris Morris]

I am considering building an ADU with a 150 square foot upstairs bedroom with a bathroom in the living room beneath, which means that, if one needs to use the bathroom in the middle of the night, one must go down the stairs to do so. My target demographic is mid term renters staying in a furnished 1 bed 1 bath (traveling nurses and other professionals, mainly).

How big of a turnoff is having to go down the stairs to use the bathroom?

Should I try to fit a 40 square foot bathroom upstairs, as well (making the bedroom 110 square feet)?

Or should I move the bathroom upstairs, thus adding 40 square feet to the living room and causing the bedroom to be 110 square feet?